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HelpTest ID: CMUMP Mumps Virus Antibodies, IgG and IgM, Spinal Fluid
Reporting Name
Mumps Virus Ab, IgG and IgM, CSFUseful For
Aiding in the diagnosis of central nervous system infection by mumps virus
Specimen Type
CSFSpecimen Required
Container/Tube: Sterile vial
Specimen Volume: 0.5 mL
Collection Instructions: Submit aliquot from collection vial 1.
Specimen Minimum Volume
0.1 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| CSF | Refrigerated (preferred) | 14 days | |
| Frozen | 14 days |
Reference Values
IgG: <1:5
IgM: <1:10
Reference values apply to all ages.
Day(s) Performed
Monday through Friday
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
86735 x 2
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| CMUMP | Mumps Virus Ab, IgG and IgM, CSF | 88458-5 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 1414 | Mumps Virus Ab, IgG | 21401-5 |
| 1415 | Mumps Virus Ab, IgM | 21402-3 |
Clinical Information
There is only one serotype of mumps virus that infects humans. Mumps has been recognized since antiquity by virtue of the parotitis, which is often a striking clinical feature of the disease. Generally, a trivial childhood illness, the varied presentation of mumps reflects the widespread invasion of visceral organs and central nervous system that commonly follows infection with mumps virus.
Interpretation
Detection of organism-specific antibodies in the cerebrospinal fluid (CSF) may suggest central nervous system infection. However, these results are unable to distinguish between intrathecal antibodies and serum antibodies introduced into the CSF at the time of lumbar puncture or from a breakdown in the blood-brain barrier. The results should be interpreted with other laboratory and clinical data prior to a diagnosis of central nervous system infection.
Clinical Reference
Litman N, Baum SG. Mumps virus. In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 9th ed. Elsevier; 2020:2087-2092
Report Available
Same day/1 to 3 daysMethod Name
Immunofluorescence
Forms
If not ordering electronically, complete, print, and send Infectious Disease Serology Test Request (T916) with the specimen.
mml-mbid-cnsinfections